Recent experimental work suggests that the concept of contextual fields should be generalized to allow the modulation of local information extraction by both external and internal context. The external context relates to the coherent information of the stimulus; the internal context refers to the parts of this information which are relevant for behavior. This dual interaction, present at every level of the hierarchy, requires a fundamental unit of processing more complex than a single neuron appears today. We argue that the (...) cortical column supplies the required mechanisms for a separate top-down and bottom-up processing and allows for interaction without destructive cross-talk. This flexibility might explain why the same basic architecture of a cortical column is used in the whole isocortex. (shrink)

Textbook descriptions of the foundations of Genetics give the impression that besides Mendel’s no other research on heredity took place during the nineteenth century. However, the publication of the Origin of Species in 1859, and the criticism that it received, placed the study of heredity at the centre of biological thought. Consequently, Herbert Spencer, Charles Darwin himself, Francis Galton, William Keith Brooks, Carl von Nägeli, August Weismann, and Hugo de Vries attempted to develop theories of heredity under an evolutionary (...) perspective, and they were all influenced by each other in various ways. Nonetheless, only Nägeli became aware of Mendel’s experimental work; it has also been questioned whether Mendel even had the intention to develop a theory of heredity. In this article, a short presentation of these theories is made, based on the original writings. The major aim of this article is to suggest that Mendel was definitely not the only one studying heredity before 1900, if he even did this, as may be inferred by textbooks. Although his work had a major impact after 1900, it had no impact during the latter half of the nineteenth century when an active community of students of heredity emerged. Thus, textbooks should not only present the work of Mendel, but also provide a wider view of the actual history and a depiction of science as a social process. (shrink)

This paper aims to give an impression of how biologists, at the turn of the twentieth century, came to conceptualize and define the hidden entities presumed to govern the process of hereditary transmission. With that, the stage was set for the emergence of genetics as a biological discipline that came to dominate the life sciences of the twentieth century. The annus mirabilis of 1900, with its triple re-appreciation of Gregor Mendel’s work by the botanists Hugo de Vries, Carl Correns, (...) and Erich Tschermak, can be seen as the watershed after which theorizing about heredity and experimentation—selecting pure lines and Mendelian crossing—became tightly connected. As to concepts before this, this paper will analyze Carl von Nägeli’s ‘idioplasm’, Hugo de Vries’s ‘pangenes’, and August Weismann’s ‘germ plasm’. Carl Correns’s Anlagen and Wilhelm Johannsen’s ‘genes’ would replace them in the decade after 1900.Keywords: Idioplasm ; Pangenes ; Germ plasm ; Anlagen ; Gene; Genotype. (shrink)

The University of Greenwich Generator is setting sail on a thrilling new journey of knowledge exchange with the launch of its first-ever podcast the Navigator. Crafted in collaboration with Lucien von Schomberg, Senior Lecturer in Creativity and Innovation at Greenwich Business School it promises to be an exciting platform for innovation, entrepreneurship, and thought-provoking conversation. The podcast aims to bridge the gap between academic insights and real-world issues in an easily digestible way. Through engaging conversations, listeners can expect to gain (...) valuable knowledge from industry leaders and academic experts alike. Operating on three key principles—knowledge communication, knowledge exchange, and knowledge creation—this podcast embodies the essence of the Generator's mission, inspiring, educating and fostering collaboration. The first episode explores the limitless potential of AI in today's world, unravelling its impact on business, education, and society. Guests share their profound insights, experiences, and practical advice, shedding light on how AI is shaping our future. The episode delved deep into the ethical implications but also vast potential of using AI in the future and how it will affect both education and the wider world. The episode boasts an impressive lineup of inaugural guests, including Jane Harrington, the Vice-Chancellor of The University of Greenwich, Carl Thomas, Enterprise Advisor, and founder of Audiowings, Ghislaine Boddington, Professor in Digital Immersion, and Neil Saunders, Senior Lecturer in Mathematical Sciences. Together, these guests provide diverse perspectives on the future of AI at the university and beyond. (shrink)

In this article, I will explore how the underlying research values of ‘openness’ and ‘mutual responsiveness’, which are central to open science practices, can be integrated into a new ethos of science. Firstly, I will revisit Robert Merton's early contribution to this issue, examining whether the ethos of science should be understood as a set of norms for scientists to practice ‘good’ science or as a set of research values as a functional requirement of the scientific system to produce knowledge, (...) irrespective of individual adherence to these norms. Secondly, I will analyse the recent codification of scientific practice in terms of ‘scientific integrity’, a framework that Merton did not pursue. Based on this analysis, and illustrated on the case of COVID-19 as a case in which the institution of science was challenged to deliver urgently on societal desirable outcomes, I will argue that promoting open science and its core norms of collaboration and openness requires broader governance of the institution of science in its relationship with society at large, rather than relying solely on self-governance within the scientific community through a new ethos of science. This conclusion has implications for re-evaluating research assessments, suggesting that the evaluation of the scientific system should take precedence over evaluating individual researchers, and that incentives should be provided to encourage specific research behaviour rather than solely focusing on individual research outputs. This article is followed up by Commentaries of Carl Mitcham, Alfred Nordmann, Sabina Leonelli, Lukas Fuchs, Monica Edwards-Schachter. (shrink)

In children experiencing pain, the study of the social context of facial expressions might help to evaluate evolutionary and conditioning hypotheses of behavioural development. Social motivations and influences may be complex, as seen in studies of children having their ears pierced, and in studies of everyday pain in children. A study of opposing predictions of the long-term effects of parental caregiving is suggested.

Light and darkness transform city buildings into surreal structures: an ordinary gray concrete building in plain daylight changes at night into a mysterious monolith or, under a blue-tinted lens, into an ethereal edifice. Swedish artist Carl Michael von Hausswolff harnessed these transformative powers of light to create a powerful spectacle that presents Chicago architecture from a wholly original perspective in this collection of striking photographs. Red Empty is the latest in a series of urban-centered works spanning from Bangkok to (...) Santa Fe in which von Hausswolff set 1000-watt red spotlights against the architecture of run-down, abandoned buildings to generate spectral real-world monochromes. His images explore intermediate realms through these otherworldly images—worlds traced by psychic residue that rewrite the history of particular sites. Red Empty is a compelling visual work that transforms Chicago architecture into sculptures of light, shadow, and stone. (shrink)

Scientists cannot take a neutral position regarding the way progress evolves. The environment, social justice and international order are the key factors for constructing peace.

Carl Schmitt (1888–1985), Professor für Staats- und Völkerrecht, bewegt nach wie vor die Gemüter. Die Reaktion auf seine Schriften, Handlungen und Ausstrahlungen ist vielfältig; die Spanne reicht von entrüsteten, für die er der Teufel in Person bleibt, über viele Zwischenstufen bis zu jenen Lesern, die ihn für einen der subtilsten, noch keineswegs ausgeloteten Geistern dieses Jahrhunderts halten. Sein Leben lang war Carl Schmitt ein passionierter Schreiber von Briefen. Meist handelte es sich um handschriftlich verfasste, die für den Schreibenden (...) die Fortsetzung eines konkreten Gespräches mit anderen Mitteln war. Das macht das authentische und die Spontanität der Schmitt-Briefe aus. Als erste Edition einer umfangreichen Korrespondenz wird in dem Buch die Korrespondenz zwischen Carl Schmitt und Armin Mohler veröffentlicht. Der Briefwechsel umfasst die Zeit von 1947 bis 1980 und enthält 280 Briefe und Karten von Carl Schmitt an Armin Mohler. Von dem Briefpartner und Herausgeber wird in der Regel aus den eigenen Briefen nur auszugsweise zitiert, sofern es für das von Carl Schmitt Geschriebene notwendig ist. Armin Mohler (1920 bis 2003), ist einer der bekanntesten rechtskonservativen Schriftsteller, Kritiker und Historiker in Deutschland. Sein Handbuch zur Konservativen Revolution ist ein Standardwerk. In der Zeit des Briefwechsels war Mohler von 1949 bis 1953 Sekretär Ernst Jüngers, danach Korrespondent großer Zeitungen in Paris und von 1964 an Geschäftsführer der Carl Friedrich von Siemens Stiftung, in der er sehr beachtete Symposien zu aktuellen wissenschaftlichen Themen organisierte. Der Briefwechsel ist für die Deutung Carl Schmitts in der Nachkriegszeit in seinem Sauerländer "Exil" grundlegend, gleichzeitig enthält er pointierte Schlaglichter auf das politische und kulturelle Geschehen der frühen und mittleren Bundesrepublik sowie auf Werk und Leben von Ernst Jünger. (shrink)

Edvard August Vainio was a world-renowned Finnish lichenologist. In Finland, however, he was a controversial person due to his strong pro-Finnish political views. Equally disputed was his opinion that systematics should be based on evolutionary theory and phylogenetic thinking. Vainio was familiar with the ideas of the early German phylogeneticists—especially those of Carl Wilhelm von Nägeli – and, applying them, aimed to create an exact method for building a natural classification of lichens already at the end of the nineteenth (...) century. In this respect, Vainio was a true pioneer, as no actual phylogenetic method had yet been developed. In the general spirit of the time, Vainio focused on finding the ancestors of species and other taxa by comparing primitive and derived features of homologous characters. However, Vainio already understood the concept of sister groups in 1880, the identification of which is the basis of all modern phylogenetic research. Nevertheless, the distinctive method developed by Vainio was not so much focused on the construction of a phylogenetic tree, but on revealing the origin of species through the differentiation and fixation of their polymorphic variation. Indeed, Vainio’s species concept is surprisingly similar to the phylogenetic species concepts presented a hundred years later. Although in many ways progressive, Vainio’s views did not influence the development of phylogenetics more widely, but his discussions are nevertheless a valuable source to understanding the early development of phylogenetic theory. (shrink)

Until quite recently, mind-body dualism has been regarded with deep suspicion by both philosophers and scientists. This has largely been due to the widespread identification of dualism in general with one particular version of it: the interactionist substance dualism of Réné Descartes. This traditional form of dualism has, ever since its first formulation in the seventeenth century, attracted numerous philosophical objections and is now almost universally rejected in scientific circles as empirically inadequate. During the last few years, however, renewed attention (...) has begun to be paid to the dualistic point of view, as a result of increasing discontent with the prevailing materialism and reductionism of contemporary scientific and philosophical thought. Awareness has grown that dualism need not be restricted to its traditional form and that other varieties of dualism are not subject to the difficulties commonly raised against Descartes' own version of it. -/- Interest in these alternative versions of dualism is growing fast today, because it seems that they are capable of capturing deep-seated philosophical intuitions, while also being fully consistent with the methodological assumptions and empirical findings of modern scientific work on the human mind and brain. The object of this book is to provide philosophers, scientists, their students, and the wider general public with an up-to-date overview of current developments in dualistic conceptions of the mind in contemporary philosophy and science. (shrink)

Das Buch enth lt 84 Briefe Spinozas, im Original 1914 erschienen.

Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)